C9394

Sigma

 

Chlorhexidine digluconate solution

20% in H2O

Synonym:1,6-Bis(N5-[p-chlorophenyl]-N1-biguanido)hexane; 1,1′-Hexamethylenebis(5-[p-chlorophenyl]biguanide)
CAS Number:18472-51-0
MDL number:MFCD00083599

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Description

Biochem/physiol ActionsCationic broad-spectrum antimicrobial agent belonging to the bis(biguanide) family. Its mechanism of action involves destabilization of the outer bacterial membrane. It is used primarily as a topical antiseptic/disinfectant in wound healing, at catheterization sites, in various dental applications and in surgical scrubs.

Properties

concentration20% in H2O
density1.06 g/mL at 25 °C(lit.)
storage temp.2-8°C

Safety

WGK GermanyNWG

References

referenceBarrett-Bee, K., et al., The membrane destabilising action of the antibacterial agent chlorhexidine. FEMS Microbiol. Lett. 119, 249-253, (1994)